2022
Nature
Unified rhombic lip origins of group 3 and group 4 medulloblastoma
cancer DNAsequencing RNAseq Methylation ATACseq single-cell ChIPseq First-author Github
2022
Mol Cancer Ther.
Combination of Ribociclib and Gemcitabine for the Treatment of Medulloblastoma. Molecular cancer therapeutics
cancer RNAseq Github
2022
NeuroOncology
Vorinostat and isotretinoin with chemotherapy in young children with embryonal brain tumors: A report from the Pediatric Brain Tumor Consortium (PBTC-026)
cancer DNAsequencing Methylation Github
2022
STAR protocols
Low-coverage whole-genome sequencing of cerebrospinal-fluid-derived cell-free DNA in brain tumor patients
cancer DNAsequencing Github
2021
Cancer Cell
Serial assessment of measurable residual disease in medulloblastoma liquid biopsies
cancer DNAsequencing Methylation First-author Github
2021
JAMA Oncology
Efficacy of carboplatin and isotretinoin in children with high-risk medulloblastoma: a randomized clinical trial from the Children’s Oncology Group
cancer DNAsequencing Methylation Github
2021
Acta Neuropathologica
Subgroup and subtype-specific outcomes in adult medulloblastoma. Acta Neuropathologica
cancer Methylation Github
2021
Cell Reports
Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination
cancer RNAseq Methylation Github
2021
Journal of Clinical Oncology
Children's oncology group phase III trial of reduced-dose and reduced-volume radiotherapy with chemotherapy for newly diagnosed average-risk medulloblastoma
cancer DNAsequencing Methylation Github
2021
Journal of Clinical Oncology
Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma
cancer DNAsequencing RNAseq Methylation First-author Github
2021
Journal of Clinical Oncology
Outcomes by clinical and molecular features in children with medulloblastoma treated with risk-adapted therapy: results of an international phase III trial (SJMB03)
cancer DNAsequencing RNAseq Methylation Github
2020
NeuroOncology
Bridging the treatment gap in infant medulloblastoma: molecularly informed outcomes of a globally feasible regimen
cancer Methylation Github
2020
Trends in Genetics
Deconstructing sonic hedgehog medulloblastoma: molecular subtypes, drivers, and beyond
cancer DNAsequencing RNAseq Methylation Github
2020
Genes and Development
Functional loss of a noncanonical BCOR–PRC1. 1 complex accelerates SHH-driven medulloblastoma formation
cancer DNAsequencing Methylation Github
2020
Developmental Cell
DDX3X suppresses the susceptibility of hindbrain lineages to medulloblastoma
cancer DNAsequencing RNAseq Methylation Github
2020
Acta Neuropathologica
Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource
cancer DNAsequencing RNAseq Methylation First-author Github
2020
NeuroOncology
SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors
cancer DNAsequencing RNAseq Methylation Github
2020
Nature
Germline elongator mutations in sonic hedgehog medulloblastoma
cancer DNAsequencing RNAseq Methylation Protein Github
2019
Nature Communications
scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy
cancer RNAseq single-cell Github
2019
Nature
Resolving medulloblastoma cellular architecture by single-cell genomics
cancer DNAsequencing RNAseq Methylation single-cell First-author Github
2018
Lancet Oncology
Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial
cancer DNAsequencing RNAseq Methylation Github
2018
Cancer Cell
NRL and CRX define photoreceptor identity and reveal subgroup-specific dependencies in medulloblastoma
cancer RNAseq Github
2017
Nat Struct Mol Biol.
Nuclear topology modulates the mutational landscapes of cancer genomes
cancer DNAsequencing First-author Github